MADE Scientific · Platform capability
Process and analytical platforms across the MADE network, grouped by unit operation and tagged with the modality each one serves. Filter to a modality to see what a program of that type would run on. Anything not yet in service says so.
Selection through fill-finish — everything that touches the product.
| Platform | Unit operation | Status | Serves |
|---|---|---|---|
| CliniMACS Prodigy Closed, automated cell processing Gates Kenderian (TSHR CAR-T) and Qin (BAFF-R CAR-T) | Selection, enrichment & wash | In service | CAR-TDCHSC |
| CliniMACS Plus CD34 and other clinical-scale selection Gates Lambert (XIAP HSC gene editing) — CD34 selection | Selection, enrichment & wash | In service | CAR-THSC |
| LOVO Automated cell wash and concentration Gates Roberts (DC, liver) and Block (FRαDC) | Selection, enrichment & wash | In service | CAR-TDCMSC |
| Elutra Counterflow elutriation, monocyte enrichment Gates Roberts (DC, liver) and Block (FRαDC) | Selection, enrichment & wash | In service | DC |
| Sepax Closed cell processing and volume reduction | Selection, enrichment & wash | In service | CAR-TDC |
| CTS Rotea Counterflow centrifugation, small to mid scale | Selection, enrichment & wash | In service | CAR-TMSC |
| Lonza 4D-Nucleofector Electroporation, research to clinical | Gene transfer | In service | CAR-THSC |
| Thermo Neon Electroporation | Gene transfer | In service | CAR-THSC |
| Thermo CTS Xenon Large-volume clinical electroporation | Gene transfer | In service | CAR-THSC |
| Flask culture T-flask, adherent and suspension | Static & gas-permeable culture | In service | MSCDCEncapsulated |
| Corning CellSTACK 2D adherent, to 40 × CS10 | Static & gas-permeable culture | In service | MSCEV |
| G-Rex Gas-permeable rapid expansion | Static & gas-permeable culture | In service | CAR-TDC |
| Gas-permeable bag culture Static closed-bag expansion | Static & gas-permeable culture | In service | CAR-TDCHSC |
| Wilson Wolf GatheRex Closed harvest from G-Rex | Static & gas-permeable culture | In service | CAR-TDC |
| PBS Biotech vertical-wheel MINI · 3 L · 15 L | Expansion — bioreactor | In service | MSCEVEncapsulated |
| Sartorius Biostat B-DCU 2–8 L stirred tank | Expansion — bioreactor | In service | MSCEVEncapsulated |
| Sartorius Biostat STR 50 L single-use stirred tank | Expansion — bioreactor | In service | MSCEVEncapsulated |
| Sartorius Ambr 15 Micro-scale parallel screening | Expansion — bioreactor | In service | MSCEV |
| Eppendorf BioFlo 320 Bench to 40 L, microcarrier and suspension | Expansion — bioreactor | In service | MSCEV |
| Xuri / WAVE W25 Rocking-motion perfusion | Expansion — bioreactor | In service | CAR-TMSC |
| Terumo Quantum Flex Hollow-fibre perfusion, adherent | Expansion — bioreactor | In service | MSC |
| Repligen KrosFlo KR2i Tangential flow filtration | Harvest, clarification & TFF | In service | EVMSC |
| Repligen KrosFlo TFDF Tangential flow depth filtration | Harvest, clarification & TFF | In service | EVMSC |
| CARR UniFuge Mini 2 Single-use continuous centrifugation | Harvest, clarification & TFF | On order | MSCEVCAR-T |
| CARR UniFuge Pilot 2 Single-use continuous centrifugation, pilot scale | Harvest, clarification & TFF | On order | MSCEV |
| Aseptic Technologies M1 Closed-vial aseptic filling | Fill-finish, cryo & lyophilization | In service | CAR-TMSCDCEVHSC |
| Manual hand fill Open manual fill under Grade A | Fill-finish, cryo & lyophilization | In service | CAR-TMSCDCEVHSC |
| High-throughput automated fill B&S / SKAN isolator-based filling | Fill-finish, cryo & lyophilization | Under evaluation | MSCEV |
| Lyophilization Millrock Technologies | Fill-finish, cryo & lyophilization | Under evaluation | EVEncapsulated |
| Controlled-rate freezer Cryopreservation to −196 °C | Fill-finish, cryo & lyophilization | In service | CAR-TMSCDCHSC |
Identity, purity, potency, safety and release testing.
| Platform | Method | Status | Serves |
|---|---|---|---|
| Beckman Coulter CytoFLEX 13-colour identity, purity and impurity | Identity & purity — flow cytometry | In service | CAR-TMSCDCHSCEncapsulated |
| Miltenyi MACSQuant Automated flow cytometry | Identity & purity — flow cytometry | In service | CAR-TDC |
| Agilent NovoCyte Flow cytometry | Identity & purity — flow cytometry | In service | CAR-TMSC |
| Accellix cytometer Cartridge-based in-process flow | Identity & purity — flow cytometry | In service | CAR-T |
| NucleoCounter NC-200/202 Automated count and viability | Cell count, viability & clonogenicity | In service | CAR-TMSCDCEncapsulated |
| Vi-CELL BLU Automated count and viability | Cell count, viability & clonogenicity | In service | MSCCAR-T |
| Nexcelom image cytometer Image-based counting | Cell count, viability & clonogenicity | In service | MSC |
| Sysmex haematology analyzer Differential haematology | Cell count, viability & clonogenicity | In service | CAR-T |
| Colony counter CFU enumeration Gates Lambert (XIAP HSC gene editing) — CFU | Cell count, viability & clonogenicity | In service | HSC |
| Bio-Rad QX200 ddPCR Droplet digital PCR, VCN and transgene | Molecular | In service | CAR-THSC |
| QuantStudio Real-time and chip digital PCR | Molecular | In service | CAR-THSCEV |
| NanoDrop One Nucleic acid and protein quantitation | Molecular | In service | EVHSC |
| Endosafe Rapid endotoxin | Safety & compendial | In service | CAR-TMSCDCEVHSCEncapsulated |
| BioFire Rapid microbial identification | Safety & compendial | In service | CAR-TMSCDC |
| SpectraMax M3 plate reader Absorbance, fluorescence, luminescence | Protein, plate & imaging | In service | MSCEV |
| Thermo plate reader Multimode plate reading | Protein, plate & imaging | In service | MSCEV |
| Varioskan Lux Multimode plate reading | Protein, plate & imaging | In service | MSCEV |
| UnChained Labs Lunatic Micro-volume protein and nucleic acid | Protein, plate & imaging | In service | EV |
| Particle Metrix ZetaView NTA — particle size and concentration | Particle characterization | In service | EV |
Nothing matches that filter.